Association of Prenatal Ambient Air Pollution Exposure With Placental Mitochondrial DNA Copy Number, Telomere Length and Preeclampsia

Association of Prenatal Ambient Air Pollution Exposure With Placental Mitochondrial DNA Copy Number, Telomere Length and Preeclampsia

Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between pren...

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Bibliographic Details
Main Authors: Yumjirmaa Mandakh, Anna Oudin, Lena Erlandsson, Christina Isaxon, Stefan R. Hansson, Karin Broberg, Ebba Malmqvist
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Toxicology
Subjects:
preeclampsia
mitochondrial DNA copy number
telomere length
nitrogen oxides
placenta
ambient air pollution
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2021.659407/full

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