Heparin Attenuates Histone-Mediated Cytotoxicity in Septic Acute Kidney Injury

Heparin Attenuates Histone-Mediated Cytotoxicity in Septic Acute Kidney Injury

Histones are considered potential risk factors that contribute to the development of septic acute kidney injury (SAKI) by inducing apoptosis and inflammation. This study aimed to explore the protective effects of heparin on septic acute kidney injury through the neutralization of extracellular histo...

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Bibliographic Details
Main Authors: Ziyi Wang, Lijun Wang, Chao Cao, Heng Jin, Yan Zhang, Yancun Liu, Yulei Gao, Xue Liang, Guangping Li, Songtao Shou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Medicine
Subjects:
heparin
histone
HK-2 cells
apoptosis
septic acute kidney injury
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.586652/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.586652/full

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