Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic Implications

Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic Implications

Fungal sulfur uptake is required for incorporation into the sidechains of the amino acids cysteine and methionine, and is also essential for the biosynthesis of the antioxidant glutathione (GSH), S-adenosylmethionine (SAM), the key source of methyl groups in cellular transmethylation reactions, and...

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Bibliographic Details
Main Authors: Aimee M. Traynor, Kevin J. Sheridan, Gary W. Jones, José A. Calera, Sean Doyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
Aspergillus
sulfur
ergothioneine
gliotoxin
zinc
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02859/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02859/full

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