Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis

Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis

The interaction between glomerular endothelial cells (GECs) and glomerular mesangial cells (GMCs) is an essential aspect of diabetic nephropathy (DN). Therefore, understanding how GECs communicate with GMCs in the diabetic environment is crucial for the development of new targets for the prevention...

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Bibliographic Details
Main Authors: Xiao-ming Wu, Yan-bin Gao, Fang-qiang Cui, Na Zhang
Format: Article
Language:English
Published: The Company of Biologists 2016-04-01
Series:Biology Open
Subjects:
Exosome
Glomerular endothelial cells
Glomerular mesangial cells
High glucose
Activation
Renal Fibrosis
Online Access:http://bio.biologists.org/content/5/4/484

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