Ameliorative Effect of Gallic Acid on Cyclophosphamide-Induced Oxidative Injury and Hepatic Dysfunction in Rats

Ameliorative Effect of Gallic Acid on Cyclophosphamide-Induced Oxidative Injury and Hepatic Dysfunction in Rats

Cyclophosphamide (CP), a bifunctional alkylating agent used in chemotherapy has been reported to induce organ toxicity mediated by generation of reactive oxygen species and oxidative stress. Gallic acid (GA), a phenolic substance, is a natural antioxidant with proven free radical scavenging activity...

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Bibliographic Details
Main Authors: Ebenezer Tunde Olayinka, Ayokanmi Ore, Olaniyi Solomon Ola, Oluwatobi Adewumi Adeyemo
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Medical Sciences
Subjects:
cyclophosphamide
gallic acid
oxidative injury
hepatic dysfunction
Online Access:http://www.mdpi.com/2076-3271/3/3/78

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