A Forward Genetic Screen and Whole Genome Sequencing Identify Deflagellation Defective Mutants in Chlamydomonas, Including Assignment of ADF1 as a TRP Channel

A Forward Genetic Screen and Whole Genome Sequencing Identify Deflagellation Defective Mutants in Chlamydomonas, Including Assignment of ADF1 as a TRP Channel

With rare exception, ciliated cells entering mitosis lose their cilia, thereby freeing basal bodies to serve as centrosomes in the formation of high-fidelity mitotic spindles. Cilia can be lost by shedding or disassembly, but either way, it appears that the final release may be via a coordinated sev...

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Bibliographic Details
Main Authors: Laura K. Hilton, Fabian Meili, Paul D. Buckoll, Julie C. Rodriguez-Pike, Courtney P. Choutka, Jaime A. Kirschner, Freda Warner, Mette Lethan, Fabian A. Garces, Jingnan Qi, Lynne M. Quarmby
Format: Article
Language:English
Published: Oxford University Press 2016-10-01
Series:G3: Genes, Genomes, Genetics
Subjects:
calcium
Chlamydomonas reinhardtii
TRP15
FAP16
Mutant Screen Report
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.034264

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.034264

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