Transcriptional Start Site Coverage Analysis in Plasma Cell-Free DNA Reveals Disease Severity and Tissue Specificity of COVID-19 Patients

Transcriptional Start Site Coverage Analysis in Plasma Cell-Free DNA Reveals Disease Severity and Tissue Specificity of COVID-19 Patients

Symptoms of coronavirus disease 2019 (COVID-19) range from asymptomatic to severe pneumonia and death. A deep understanding of the variation of biological characteristics in severe COVID-19 patients is crucial for the detection of individuals at high risk of critical condition for the clinical manag...

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Bibliographic Details
Main Authors: Xinping Chen, Tao Wu, Lingguo Li, Yu Lin, Zhichao Ma, Jinjin Xu, Hui Li, Fanjun Cheng, Ruoyan Chen, Kun Sun, Yuxue Luo, Chen Zhang, Fang Chen, Jiao Wang, Tingyu Kuo, Xiaojuan Li, Chunyu Geng, Feng Lin, Chaojie Huang, Junjie Hu, Jianhua Yin, Ming Liu, Ye Tao, Jiye Zhang, Rijing Ou, Fang Zheng, Yan Jin, Huanming Yang, Jian Wang, Xun Xu, Shengmiao Fu, Hongyan Jiang, Xin Jin, Haiqiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
plasma DNA
TSS coverage
SARS-CoV-2
tissue specificity
COVID-19 severity
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.663098/full

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