The 5′ Untranslated Region of the EFG1 Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in Candida albicans

The 5′ Untranslated Region of the EFG1 Transcript Promotes Its Translation To Regulate Hyphal Morphogenesis in Candida albicans

Many of the virulence traits that make Candida albicans an important human fungal pathogen are regulated on a transcriptional level. Here, we report an important regulatory contribution of translation, which is exerted by the extensive 5′ untranslated regulatory sequence (5′ UTR) of the transcript f...

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Bibliographic Details
Main Authors: Prashant R. Desai, Klaus Lengeler, Mario Kapitan, Silas Matthias Janßen, Paula Alepuz, Ilse D. Jacobsen, Joachim F. Ernst
Format: Article
Language:English
Published: American Society for Microbiology 2018-07-01
Series:mSphere
Subjects:
5′ UTR
Candida albicans
EFG1
filamentation
hyphal morphogenesis
posttranscriptional regulation
translation
Online Access:https://doi.org/10.1128/mSphere.00280-18

Internet

https://doi.org/10.1128/mSphere.00280-18

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