Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection.

Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection.

Translational errors can result in bypassing of the main viral protein reading frames and the production of alternate reading frame (ARF) or cryptic peptides. Within HIV, there are many such ARFs in both sense and the antisense directions of transcription. These ARFs have the potential to generate i...

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Bibliographic Details
Main Authors: Stephane Champiat, Rui André Saraiva Raposo, Nicholas J Maness, John L Lehman, Sean E Purtell, Aaron M Hasenkrug, Jacob C Miller, Hansi Dean, Wayne C Koff, Marisa Ailin Hong, Jeffrey N Martin, Steven G Deeks, Gerald E Spotts, Christopher D Pilcher, Fredrick M Hecht, Esper G Kallas, Keith E Garrison, Douglas F Nixon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387156?pdf=render

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