SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography

Early and accurate diagnosis of glaucoma is critical for avoiding human vision deterioration and preventing blindness. A deep-neural-network model has been developed for the diagnosis of glaucoma based on Heidelberg retina tomography (HRT), called “Seeking Common Features and Reserving Differences N...

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Main Authors: Hua Wang, Jingfei Hu, Jicong Zhang
Format: Article
Language:English
Published: Hindawi-Wiley 2021-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2021/9858343
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spelling doaj-fe8cd73d353e4a079478bd5d988c70002021-04-19T00:05:25ZengHindawi-WileyComplexity1099-05262021-01-01202110.1155/2021/9858343SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina TomographyHua Wang0Jingfei Hu1Jicong Zhang2School of Biological Science and Medical EngineeringSchool of Biological Science and Medical EngineeringSchool of Biological Science and Medical EngineeringEarly and accurate diagnosis of glaucoma is critical for avoiding human vision deterioration and preventing blindness. A deep-neural-network model has been developed for the diagnosis of glaucoma based on Heidelberg retina tomography (HRT), called “Seeking Common Features and Reserving Differences Net” (SCRD-Net) to make full use of the HRT data. In this work, the proposed SCRD-Net model achieved an area under the curve (AUC) of 94.0%. For the two HRT image modalities, the model sensitivities were 91.2% and 78.3% at specificities of 0.85 and 0.95, respectively. These results demonstrate a significant improvement over earlier results. In addition, we visualized the network outputs to develop an interpretation of the learned mechanism for discriminating glaucoma and normal images. Thus, the SCRD-Net can be an effective diagnostic indicator of glaucoma during clinical screening. To facilitate SCRD-Net utilization by the scientific community, the code implementation will be made publicly available.http://dx.doi.org/10.1155/2021/9858343
collection DOAJ
language English
format Article
sources DOAJ
author Hua Wang
Jingfei Hu
Jicong Zhang
spellingShingle Hua Wang
Jingfei Hu
Jicong Zhang
SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography
Complexity
author_facet Hua Wang
Jingfei Hu
Jicong Zhang
author_sort Hua Wang
title SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography
title_short SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography
title_full SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography
title_fullStr SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography
title_full_unstemmed SCRD-Net: A Deep Convolutional Neural Network Model for Glaucoma Detection in Retina Tomography
title_sort scrd-net: a deep convolutional neural network model for glaucoma detection in retina tomography
publisher Hindawi-Wiley
series Complexity
issn 1099-0526
publishDate 2021-01-01
description Early and accurate diagnosis of glaucoma is critical for avoiding human vision deterioration and preventing blindness. A deep-neural-network model has been developed for the diagnosis of glaucoma based on Heidelberg retina tomography (HRT), called “Seeking Common Features and Reserving Differences Net” (SCRD-Net) to make full use of the HRT data. In this work, the proposed SCRD-Net model achieved an area under the curve (AUC) of 94.0%. For the two HRT image modalities, the model sensitivities were 91.2% and 78.3% at specificities of 0.85 and 0.95, respectively. These results demonstrate a significant improvement over earlier results. In addition, we visualized the network outputs to develop an interpretation of the learned mechanism for discriminating glaucoma and normal images. Thus, the SCRD-Net can be an effective diagnostic indicator of glaucoma during clinical screening. To facilitate SCRD-Net utilization by the scientific community, the code implementation will be made publicly available.
url http://dx.doi.org/10.1155/2021/9858343
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