Presence of Immune Complexes of IgG/IgM Bound to B2-glycoprotein I Is Associated With Non-criteria Clinical Manifestations in Patients With Antiphospholipid Syndrome

Presence of Immune Complexes of IgG/IgM Bound to B2-glycoprotein I Is Associated With Non-criteria Clinical Manifestations in Patients With Antiphospholipid Syndrome

Background: Antiphospholipid syndrome (APS) is an acquired autoimmune disorder defined by the presence of both clinical (thromboembolic events or pregnancy morbidity) and laboratory (antiphospholipid antibodies, aPL) manifestations. Despite their importance, several clinical manifestations strongly...

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Bibliographic Details
Main Authors: Dolores Pérez, Ljudmila Stojanovich, Laura Naranjo, Natasa Stanisavljevic, Gordana Bogdanovic, Manuel Serrano, Antonio Serrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
antiphospholipid
livedo reticularis
sicca
thrombocytopenia
leukopenia
circulating immune-complexes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02644/full

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