HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material

HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material

Abstract Background HMGB1 is a mediator of systemic inflammation in sepsis and trauma, and a promising biomarker in many diseases. There is currently no standard operating procedure for pre-analytical handling of HMGB1 samples, despite that pre-analytical conditions account for a substantial part of...

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Bibliographic Details
Main Authors: William Ottestad, Ingrid N. Rognes, Erlend Skaga, Cassandra Frisvoll, Guttorm Haraldsen, Torsten Eken, Peter Lundbäck
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Medicine
Subjects:
HMGB1 protein
Pre-analytical phase
Wounds and injuries
Enzyme-linked immunosorbent assay
Blotting, western
Online Access:https://doi.org/10.1186/s10020-019-0131-0

Internet

https://doi.org/10.1186/s10020-019-0131-0

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