Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells

Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells

Wedelolactone is a multi-target natural plant coumestan exhibiting cytotoxicity towards cancer cells. Although several molecular targets of wedelolactone have been recognized, the molecular mechanism of its cytotoxicity has not yet been elucidated. In this study, we show that wedelolactone acts as a...

Full description

Bibliographic Details
Main Authors: Tereza Nehybová, Jan Šmarda, Lukáš Daniel, Marek Stiborek, Viktor Kanický, Ivan Spasojevič, Jan Preisler, Jiří Damborský, Petr Beneš
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
copper
proteasome
reactive oxygen species
wedelolactone
Online Access:http://www.mdpi.com/1422-0067/18/4/729

Similar Items

Similar Items