Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions

Genome-wide mapping of chromatin interactions reveals various levels of 3D genome organization. Here, the authors develop SNIPER, a computational method for identifying subcompartments using Hi-C data with moderate coverage.

Bibliographic Details
Main Authors: Kyle Xiong, Jian Ma
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12954-4