A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse

A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse

Fabry disease is a rare lysosomal storage disorder resulting from the lack of α-Gal A gene activity. Globotriaosylceramide (GB3, ceramide trihexoside) is a novel endogenous biomarker which predicts the incidence of Fabry disease. At the early stage efficacy/biomarker study, a rapid method...

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Bibliographic Details
Main Authors:	Seok-Ho Shin, Min-Ho Park, Jin-Ju Byeon, Byeong ill Lee, Yuri Park, Ah-ra Ko, Mi-ran Seong, Soyeon Lee, Mi Ra Kim, Jinwook Seo, Myung Eun Jung, Dong-Kyu Jin, Young G. Shin
Format:	Article
Language:	English
Published:	MDPI AG 2018-06-01
Series:	Pharmaceutics
Subjects:	GB3 Fabry disease LC-QTOF-MS/MS B6 129-Glatm1Kul/J
Online Access:	http://www.mdpi.com/1999-4923/10/2/69

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