Hyperoxalemia Leads to Oxidative Stress in Endothelial Cells and Mice with Chronic Kidney Disease

Hyperoxalemia Leads to Oxidative Stress in Endothelial Cells and Mice with Chronic Kidney Disease

Introduction: Cardiovascular disease is the most common cause of morbidity and mortality in patients with ESRD. In addition to phosphate overload, oxalate, a common uremic toxin, is also involved in vascular calcification in patients with ESRD. The present study investigated the role and mechanism o...

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Bibliographic Details
Main Authors: Ke Sun, Xiaojing Tang, Shuwei Song, Yuan Gao, Hongjing Yu, Ningyun Sun, Bin Wen, Changlin Mei
Format: Article
Language:English
Published: Karger Publishers 2021-05-01
Series:Kidney & Blood Pressure Research
Subjects:
end-stage renal disease
hyperoxalemia
vascular calcification
oxidative stress
Online Access:https://www.karger.com/Article/FullText/516013

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