Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity
Both inhibitory and excitatory input development are shaped by activity, but one may be dependent on the other. Here, the authors examine plasticity of inhibitory inputs in vivo, as well as behavioral consequences in tadpoles where excitatory transmission has been impaired.
Main Authors: | Hai-yan He, Wanhua Shen, Lijun Zheng, Xia Guo, Hollis T. Cline |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05125-4 |
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