Imbalance between pro and anti-oxidant mechanisms in perivascular adipose tissue aggravates long-term high-fat diet-derived endothelial dysfunction.

Imbalance between pro and anti-oxidant mechanisms in perivascular adipose tissue aggravates long-term high-fat diet-derived endothelial dysfunction.

BACKGROUND: The hypothesis of this study is that long-term high-fat diets (HFD) induce perivascular adipose tissue (PVAT) dysfunction characterized by a redox imbalance, which might contribute to aggravate endothelial dysfunction in obesity. METHODS AND RESULTS: C57BL/6J mice were fed either control...

Full description

Bibliographic Details
Main Authors: Marta Gil-Ortega, Luis Condezo-Hoyos, Concha F García-Prieto, Silvia M Arribas, M Carmen González, Isabel Aranguez, Mariano Ruiz-Gayo, Beatriz Somoza, María S Fernández-Alfonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3997398?pdf=render

Internet

http://europepmc.org/articles/PMC3997398?pdf=render

Similar Items