The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against <it>Toxoplasma gondii</it>

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against <it>Toxoplasma gondii</it>

<p>Abstract</p> <p>Background</p> <p>The interferon-inducible immunity-related GTPases (IRG proteins/p47 GTPases) are a distinctive family of GTPases that function as powerful cell-autonomous resistance factors. The IRG protein, Irga6 (IIGP1), participates in the disrup...

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Bibliographic Details
Main Authors: Uthaiah Revathy C, Schmidt Andreas, Papic Natasa, Hunn Julia P, Khaminets Aliaksandr, Pawlowski Nikolaus, Lange Rita, Vopper Gabriela, Martens Sascha, Wolf Eva, Howard Jonathan C
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/7

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