Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action
Abstract Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only two aluminium salts which are used in clinically-approved vaccines, Alhydrogel® and AdjuPhos®, while the novel aluminium adjuvant used in Gardasil® is a sulphated version of the latter. We have investiga...
Main Authors: | Emma Shardlow, Matthew Mold, Christopher Exley |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | Allergy, Asthma & Clinical Immunology |
Online Access: | http://link.springer.com/article/10.1186/s13223-018-0305-2 |
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