Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action

Abstract Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only two aluminium salts which are used in clinically-approved vaccines, Alhydrogel® and AdjuPhos®, while the novel aluminium adjuvant used in Gardasil® is a sulphated version of the latter. We have investiga...

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Bibliographic Details
Main Authors: Emma Shardlow, Matthew Mold, Christopher Exley
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:http://link.springer.com/article/10.1186/s13223-018-0305-2

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