Andrographolide Sulfonate Is a Promising Treatment to Combat Methicillin-resistant Staphylococcus aureus and Its Biofilms

Andrographolide Sulfonate Is a Promising Treatment to Combat Methicillin-resistant Staphylococcus aureus and Its Biofilms

Methicillin-resistant Staphylococcus aureus (MRSA) is a drug-resistant pathogen threatening human health and safety. Biofilms are an important cause of its drug resistance and pathogenicity. Inhibition and elimination of biofilms is an important strategy for the treatment of MRSA infection. Androgra...

Full description

Bibliographic Details
Main Authors:	Lulu Zhang, Bo Wen, Mei Bao, Yungchi Cheng, Tariq Mahmood, Weifeng Yang, Qing Chen, Lang Lv, Li Li, Jianfeng Yi, Ning Xie, Cheng Lu, Yong Tan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Series:	Frontiers in Pharmacology
Subjects:	andrographolide sulfonate methicillin-resistant Staphylococcus aureus drug-resistant biofilm RT-PCR metabonomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.720685/full

Similar Items

Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia
by: Guorong Zhang, et al.
Published: (2019-09-01)

Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice
by: Fei Gao, et al.
Published: (2018-08-01)

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways
by: Shuang Peng, et al.
Published: (2016-05-01)

Andrographolide sulfonate attenuates alveolar hypercoagulation and fibrinolytic inhibition partly via NF-κB pathway in LPS-induced acute respiratory distress syndrome in mice
by: Hong Qian, et al.
Published: (2021-11-01)

QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors
by: Shaohui Cai, et al.
Published: (2010-03-01)

Semisynthesis and cytotoxic activities of andrographolide analogues
by: Hamzah, A.S, et al.

THE APPLICATION OF HYDROTROPES AS MEDIUM IN THE EXTRACTION OF ANDROGRAPHOLIDE
by: Indah Hartati, et al.
Published: (2014-10-01)

Mechanizms of Methicillin Resistance in Staphylococci and Methods Used in The Diagnosis of Methicillin Resistance
by: Serhat ÜNAL
Published: (1996-03-01)

Protective effects of andrographolide against diclofenac-induced gastric damage
by: Augustine Tandoh, et al.
Published: (2021-09-01)

Reaction Characteristics of Andrographolide and its Analogue AL-1 with GSH, as a Simple Chemical Simulation of NF-κB Inhibition
by: Yuqiang Wang, et al.
Published: (2012-01-01)

adioiodination of andrographolide and its biodistribution in mice for inflammatory tracer
by: Jutti Levita, et al.
Published: (2010-10-01)

Oral Bioavailability Enhancement and Anti-Fatigue Assessment of the Andrographolide Loaded Solid Dispersion
by: Ching-Chi Yen, et al.
Published: (2020-04-01)

Molecular detection and typing of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci isolated from cattle, animal handlers, and their environment from Karnataka, Southern Province of India
by: Nimita Venugopal, et al.
Published: (2019-11-01)

Andrographolide, a Natural Antioxidant: An Update
by: Eugenie Mussard, et al.
Published: (2019-11-01)

Andrographolide Ameliorates Rheumatoid Arthritis by Regulating the Apoptosis–NETosis Balance of Neutrophils
by: Xiaohong Li, et al.
Published: (2019-10-01)

Effect of Carrier Lipophilicity and Preparation Method on the Properties of Andrographolide–Solid Dispersion
by: Guowei Zhao, et al.
Published: (2019-02-01)

Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide
by: Yen CC, et al.
Published: (2018-01-01)

Andrographolide Attenuates LPS-Induced Cardiac Malfunctions Through Inhibition of IκB Phosphorylation and Apoptosis in Mice
by: Jinlong Zhang, et al.
Published: (2015-11-01)

Biodegradable andrographolide-eluting nanofibrous membranes for the treatment of cervical cancer
by: Chen YP, et al.
Published: (2019-01-01)

Methicillin-resistant Staphylococcus aureus (MRSA) in East Africa: red alert or red herring?
by: Frederick K. Wangai, et al.
Published: (2019-07-01)

Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells
by: Junqian Zhang, et al.
Published: (2021-04-01)

Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity
by: Zhang H, et al.
Published: (2019-05-01)

Two Novel Bacteriophages Control Multidrug- and Methicillin-Resistant Staphylococcus pseudintermedius Biofilm
by: Sang Guen Kim, et al.
Published: (2021-03-01)

Microwave-Assisted Synthesis of Andrographolide Analogues as Potent β-Glycosidase Inhibitors
by: Masood ur Rahman, et al.
Published: (2018-04-01)

Andrographolide Exerts Pro-Osteogenic Effect by Activation of Wnt/β-Catenin Signaling Pathway in Vitro
by: Tongmeng Jiang, et al.
Published: (2015-07-01)

Antifertility studies of curcumin and andrographolide combination in female rats
by: Nishant Shinde, et al.
Published: (2015-09-01)

Nasal colonization in children with community acquired methicillin-resistant Staphylococcus aureus
by: Fazlollah Davoodabadi, et al.
Published: (2016-01-01)

Methicillin-resistant Staphylococcus aureus, Pakistan, 1996–2003
by: Tariq Butt, et al.
Published: (2004-09-01)

A review for the neuroprotective effects of andrographolide in the central nervous system
by: Jiashu Lu, et al.
Published: (2019-09-01)

Prevalence of Methicillin and Vancomycin resistant Staphylococcus aureus colonization in nasopharynx; Amir-Alam hospital, 2005
by: Hasibi M, et al.
Published: (2007-07-01)

In-vitro susceptibility of methicillin-resistant Staphylococcus aureus strains to antibiotics
by: İsmail Güler, et al.
Published: (2011-12-01)

Quantification of Andrographolide Isolated from <i>Andrographis paniculata</i> Nees Obtained from Traditional Market in Yogyakarta Using Validated HPLC
by: Yandi Syukri, et al.
Published: (2016-08-01)

Andrographolide, an Anti-Inflammatory Multitarget Drug: All Roads Lead to Cellular Metabolism
by: Rafael Agustín Burgos, et al.
Published: (2021-12-01)

Andrographolide Ameliorate Rheumatoid Arthritis by Promoting the Development of Regulatory T Cells
by: Muhaimin Rifa’i
Published: (2010-10-01)

Molecular Epidemiology of Clinical and Colonizing Methicillin-Resistant Staphylococcus Isolates in Companion Animals
by: Hester Rynhoud, et al.
Published: (2021-04-01)

Andrographolide Alleviates Acute Brain Injury in a Rat Model of Traumatic Brain Injury: Possible Involvement of Inflammatory Signaling
by: Li Tao, et al.
Published: (2018-09-01)

Detection of Biocides Resistance Genes among Clinical Isolates of Both Methicillin-Resistant and Methicillin-Sensitive Strains of Staphylococcus Aureus
by: Walid Sabry, et al.
Published: (2021-07-01)

Andrographolide from the herb Andrographis paniculata induces apoptosis on cultured human leukemic cells
by: Hiroki Doi, et al.
Published: (2017-09-01)

Andrographolide Inhibits Ovariectomy-Induced Bone Loss via the Suppression of RANKL Signaling Pathways
by: Tao Wang, et al.
Published: (2015-11-01)

Methicillin-resistant coagulase-negative staphylococci from healthy dogs in Nsukka, Nigeria
by: Kennedy F. Chah, et al.
Published: (2014-01-01)

Cannot write session to /tmp/vufind_sessions/sess_0h2lj3ilv9i3751gfl54og1t5i