Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines.

Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines.

OBJECTIVE: To investigate the effect of CoenzymeQ10 (CoQ10) on pain severity and cartilage degeneration in an experimental model of rat osteoarthritis (OA). MATERIALS AND METHODS: OA was induced in rats by intra-articular injection of monosodium iodoacetate (MIA) to the knee. Oral administration of...

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Bibliographic Details
Main Authors: Jennifer Lee, Yeon Sik Hong, Jeong Hee Jeong, Eun Ji Yang, Joo Yeon Jhun, Mi Kyoung Park, Young Ok Jung, Jun Ki Min, Ho Youn Kim, Sung Hwan Park, Mi-La Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3718733?pdf=render

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http://europepmc.org/articles/PMC3718733?pdf=render

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