Characterization of susceptibility variants of poliovirus grown in the presence of favipiravir

Characterization of susceptibility variants of poliovirus grown in the presence of favipiravir

Background: T-705 (favipiravir) is a potent inhibitor of RNA-dependent RNA polymerases of influenza viruses and no favipiravir-resistant virus has been isolated. Poliovirus RNA polymerase has been well characterized and isolation of resistant virus was examined in poliovirus. Methods: Susceptibility...

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Bibliographic Details
Main Authors: Tohru Daikoku, Mineyuki Mizuguchi, Takayuki Obita, Takeshi Yokoyama, Yoshihiro Yoshida, Masaya Takemoto, Kimiyasu Shiraki
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Microbiology, Immunology and Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118217301007

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