Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge

Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge

Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC...

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Main Author: Maria Vergoulidou
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Biomarker Insights
Online Access:https://doi.org/10.1177/1177271917695237
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spelling doaj-fe3458b4cc30429d9f094f1a6965e4742020-11-25T03:00:05ZengSAGE PublishingBiomarker Insights1177-27192017-03-011210.1177/117727191769523710.1177_1177271917695237Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical ChallengeMaria VergoulidouLeptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges.https://doi.org/10.1177/1177271917695237
collection DOAJ
language English
format Article
sources DOAJ
author Maria Vergoulidou
spellingShingle Maria Vergoulidou
Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
Biomarker Insights
author_facet Maria Vergoulidou
author_sort Maria Vergoulidou
title Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_short Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_full Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_fullStr Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_full_unstemmed Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_sort leptomeningeal carcinomatosis in gastric cancer: a therapeutical challenge
publisher SAGE Publishing
series Biomarker Insights
issn 1177-2719
publishDate 2017-03-01
description Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges.
url https://doi.org/10.1177/1177271917695237
work_keys_str_mv AT mariavergoulidou leptomeningealcarcinomatosisingastriccanceratherapeuticalchallenge
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