Functional genetic variants in DC-SIGNR are associated with mother-to-child transmission of HIV-1.

Functional genetic variants in DC-SIGNR are associated with mother-to-child transmission of HIV-1.

BACKGROUND: Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Given that the C-type lectin receptor, dendritic cell-specific ICAM-grabbing non-integrin-related (DC-SIGNR, also known as CD209L or liver/lymph node-specific ICAM-grabbing non-integrin (L-SIG...

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Bibliographic Details
Main Authors: Geneviève Boily-Larouche, Anne-Laure Iscache, Lynn S Zijenah, Jean H Humphrey, Andrew J Mouland, Brian J Ward, Michel Roger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2752805?pdf=render

Internet

http://europepmc.org/articles/PMC2752805?pdf=render

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