Inhibition of PD-1 protein by the CRISPR-Cas9 method as antitumor therapy of non-small cell lung cancers

Lung carcinoma is the second most common type of tumor in the world. Among them, 85% of the cases are of non-small cell lung cancer (NSCLC). It is known that, in general, NSCLC tumor cells proliferate due to a reduction in the cytotoxic T lymphocyte response. In the immune response to tumors, the in...

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Bibliographic Details
Main Authors: Alison Felipe Bordini Biggi, Patricia Ucelli Simioni
Format: Article
Language:Portuguese
Published: Pontifícia Universidade Católica de São Paulo 2019-06-01
Series:Revista da Faculdade de Ciências Médicas de Sorocaba
Subjects:
Online Access:http://revistas.pucsp.br/RFCMS/article/view/38943