Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD...

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Main Authors: Ahmad Al-Attar, Steven R. Presnell, Charlotte A. Peterson, D. Travis Thomas, Charles T. Lutz
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340916303742
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spelling doaj-fe2150544ead475f92b3c560d790c86d2020-11-24T22:09:53ZengElsevierData in Brief2352-34092016-09-018536544Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humansAhmad Al-Attar0Steven R. Presnell1Charlotte A. Peterson2D. Travis Thomas3Charles T. Lutz4Department of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USADepartment of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USADepartment of Rehabilitation Sciences, College of Health Sciences, University of Kentucky, Lexington, KY, USADepartment of Clinical Sciences, College of Health Sciences, University of Kentucky, Lexington, KY, USADepartment of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA; Department of Microbiology, Immunology and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, KY, USA; Corresponding author.We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)−4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1]. Keywords: NK cell, Ageing, Cytomegalovirus, T cell, Sex factors, Vitamin D, C-reactive protein, Adiponectin, IL-15, Sphingosine-1-phosphate, Retinol binding protein-4http://www.sciencedirect.com/science/article/pii/S2352340916303742
collection DOAJ
language English
format Article
sources DOAJ
author Ahmad Al-Attar
Steven R. Presnell
Charlotte A. Peterson
D. Travis Thomas
Charles T. Lutz
spellingShingle Ahmad Al-Attar
Steven R. Presnell
Charlotte A. Peterson
D. Travis Thomas
Charles T. Lutz
Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans
Data in Brief
author_facet Ahmad Al-Attar
Steven R. Presnell
Charlotte A. Peterson
D. Travis Thomas
Charles T. Lutz
author_sort Ahmad Al-Attar
title Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans
title_short Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans
title_full Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans
title_fullStr Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans
title_full_unstemmed Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans
title_sort data correlations between gender, cytomegalovirus infection and t cells, nk cells, and soluble immune mediators in elderly humans
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2016-09-01
description We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56dim NK cell responses to a variety of stimuli and with CD56bright/CD56dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)−4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1]. Keywords: NK cell, Ageing, Cytomegalovirus, T cell, Sex factors, Vitamin D, C-reactive protein, Adiponectin, IL-15, Sphingosine-1-phosphate, Retinol binding protein-4
url http://www.sciencedirect.com/science/article/pii/S2352340916303742
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