Comparison of Tacrolimus and Sirolimus Based Regimens on Regulatory T Cell Levels in Renal Transplant Recipients: A Study from a Tertiary Care Centre in Kerala, India

Comparison of Tacrolimus and Sirolimus Based Regimens on Regulatory T Cell Levels in Renal Transplant Recipients: A Study from a Tertiary Care Centre in Kerala, India

Introduction: A subset of CD4 lymphocytes known as regulatory T (Treg) cells is known to downregulate the immune system. If their levels are raised, immune tolerance can be increased. It was seen that certain drugs like tacrolimus (calcineurin inhibitor) and sirolimus (mTOR inhibitor) used for immun...

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Bibliographic Details
Main Authors: Roshan Nasimudeen, Saji Francis, Melemadathil Sreelatha, Sathi Puthenparambath
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2019-10-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
calcineurin inhibitors
flow cytometry
immune tolerance
immunosuppression
Online Access:https://jcdr.net/articles/PDF/13190/42355_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SL).pdf

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