The influence of testosterone level in male rats on gastrotoxicity of non-steroidal anti-inflammatory drugs (NSAIDs)

The influence of testosterone level in male rats on gastrotoxicity of non-steroidal anti-inflammatory drugs (NSAIDs)

In experiments on male rats the influence of different degree of saturation of rats organism with testosterone on gastrotoxicity of diclophenac-sodium, nomesulide and celecoxib was investigated. It was shown that testosterone promoted increase of damaging action of NSAIDs on the stomach. After gonad...

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Bibliographic Details
Main Author: Voloshchuk N.I.
Format: Article
Language:English
Published: SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine" 2013-06-01
Series:Medičnì Perspektivi
Subjects:
gastrotoxicity
rats
testosterone
diclophenac
nimesulid
celecoxib
Online Access:http://medpers.dsma.dp.ua/issues/2013/N2/09-16.pdf

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