Overexpression of Limb-Bud and Heart (LBH) promotes angiogenesis in human glioma via VEGFA-mediated ERK signalling under hypoxia

Background: Glioma is the most common primary malignant tumor in the central nervous system with frequent hypoxia and angiogenesis. Limb-Bud and Heart (LBH) is a highly conserved transcription cofactor that participates in embryonic development and tumorigenesis. Methods: The conditioned media from...

Full description

Bibliographic Details
Main Authors: Yang Jiang, Jinpeng Zhou, Dan Zou, Dianqi Hou, Haiying Zhang, Junshuang Zhao, Long Li, Jiangfeng Hu, Ye Zhang, Zhitao Jing
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419306383