Lower-order effects adjustment in quantitative traits model-based multifactor dimensionality reduction.

Lower-order effects adjustment in quantitative traits model-based multifactor dimensionality reduction.

Identifying gene-gene interactions or gene-environment interactions in studies of human complex diseases remains a big challenge in genetic epidemiology. An additional challenge, often forgotten, is to account for important lower-order genetic effects. These may hamper the identification of genuine...

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Bibliographic Details
Main Authors: Jestinah M Mahachie John, Tom Cattaert, François Van Lishout, Elena S Gusareva, Kristel Van Steen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3252336?pdf=render

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