Modern Trends in Imaging VI: Raman Scattering in Pathology

Raman scattering is the inelastic scattering of light by chemical bonds, and can therefore show molecular specificity. It can be used both in pure spectroscopy mode, and in imaging mode. While many applications of Raman spectroscopy and imaging in the biomedical field have been so far demonstrated,...

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Main Authors: Zachary J. Smith, Thomas R. Huser, Sebastian Wachsmann-Hogiu
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2011-0048
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spelling doaj-fdf0ff11fd5b4f6eb488fdcad8a74c682021-07-02T04:36:19ZengHindawi LimitedAnalytical Cellular Pathology2210-71772210-71852012-01-0135314516310.3233/ACP-2011-0048Modern Trends in Imaging VI: Raman Scattering in PathologyZachary J. Smith0Thomas R. Huser1Sebastian Wachsmann-Hogiu2Center for Biophotonic Science and Technology, University of California, Davis, CA, USACenter for Biophotonic Science and Technology, University of California, Davis, CA, USACenter for Biophotonic Science and Technology, University of California, Davis, CA, USARaman scattering is the inelastic scattering of light by chemical bonds, and can therefore show molecular specificity. It can be used both in pure spectroscopy mode, and in imaging mode. While many applications of Raman spectroscopy and imaging in the biomedical field have been so far demonstrated, the use of this technology for pathology applications is still in early stages. In this paper we review some of the most important recent developments in this field, including a description of relevant technologies, applications to molecular sensing, characterization of cells and tissues of interest, and disease detection via Raman scattering.http://dx.doi.org/10.3233/ACP-2011-0048
collection DOAJ
language English
format Article
sources DOAJ
author Zachary J. Smith
Thomas R. Huser
Sebastian Wachsmann-Hogiu
spellingShingle Zachary J. Smith
Thomas R. Huser
Sebastian Wachsmann-Hogiu
Modern Trends in Imaging VI: Raman Scattering in Pathology
Analytical Cellular Pathology
author_facet Zachary J. Smith
Thomas R. Huser
Sebastian Wachsmann-Hogiu
author_sort Zachary J. Smith
title Modern Trends in Imaging VI: Raman Scattering in Pathology
title_short Modern Trends in Imaging VI: Raman Scattering in Pathology
title_full Modern Trends in Imaging VI: Raman Scattering in Pathology
title_fullStr Modern Trends in Imaging VI: Raman Scattering in Pathology
title_full_unstemmed Modern Trends in Imaging VI: Raman Scattering in Pathology
title_sort modern trends in imaging vi: raman scattering in pathology
publisher Hindawi Limited
series Analytical Cellular Pathology
issn 2210-7177
2210-7185
publishDate 2012-01-01
description Raman scattering is the inelastic scattering of light by chemical bonds, and can therefore show molecular specificity. It can be used both in pure spectroscopy mode, and in imaging mode. While many applications of Raman spectroscopy and imaging in the biomedical field have been so far demonstrated, the use of this technology for pathology applications is still in early stages. In this paper we review some of the most important recent developments in this field, including a description of relevant technologies, applications to molecular sensing, characterization of cells and tissues of interest, and disease detection via Raman scattering.
url http://dx.doi.org/10.3233/ACP-2011-0048
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