Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma

Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma

Abstract Background Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6), a key protein involved in synthetizing dihydrotestosterone, is abundant in the liver. Previous studies have suggested a role for dihydrotestosterone in modulating progress of various malignancies, and HSD17B6 dysfunction was assoc...

Full description

Bibliographic Details
Main Authors: Lei Lv, Yujia Zhao, Qinqin Wei, Ye Zhao, Qiyi Yi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cancer Cell International
Subjects:
HSD17B6
HNF4A
DNA methylation
Hepatocellular carcinoma (HCC)
Androgen
Immune suppression
Online Access:http://link.springer.com/article/10.1186/s12935-020-01298-5

Internet

http://link.springer.com/article/10.1186/s12935-020-01298-5

Similar Items