Circulating Methylated XAF1 DNA Indicates Poor Prognosis for Gastric Cancer.

Circulating Methylated XAF1 DNA Indicates Poor Prognosis for Gastric Cancer.

BACKGROUND:Methylated DNA in fluids may be a suitable biomarker for cancer patients. XAF1 has been shown to be frequently down-regulated in human gastric cancer (GC). Here, we investigated if XAF1 methylation in GC could be a useful biomarker. METHODS:Real-time RT-PCR was used to detect XAF1 mRNA ex...

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Bibliographic Details
Main Authors: Zhi-Qiang Ling, Ping Lv, Xiao-Xiao Lu, Jiang-Liu Yu, Jing Han, Li-Sha Ying, Xin Zhu, Wang-Yu Zhu, Xian-Hua Fang, Shi Wang, Yi-Chen Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3695092?pdf=render

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