An Exploratory Evaluation of Tyrosine Hydroxylase Inhibition in Planaria as a Model for Parkinsonism

An Exploratory Evaluation of Tyrosine Hydroxylase Inhibition in Planaria as a Model for Parkinsonism

Planaria are the simplest organisms with bilateral symmetry and a central nervous system (CNS) with cephalization; therefore, they could be useful as model organisms to investigate mechanistic aspects of parkinsonism and to screen potential therapeutic agents. Taking advantage of the organism’s anti...

Full description

Bibliographic Details
Main Authors: David Prokai, Thinh Nguyen, Kurt Kamrowski, Ashwin Chandra, Tatjana Talamantes, Lewis R. Baxter, Laszlo Prokai
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
planaria
parkinsonism
tyrosine hydroxylase
monoiodotyrosine
bromocriptine
antiparkinsonian agent
Online Access:http://www.mdpi.com/1422-0067/14/12/23289

Internet

http://www.mdpi.com/1422-0067/14/12/23289

Similar Items