Visfatin is regulated by rosiglitazone in type 2 diabetes mellitus and influenced by NFκB and JNK in human abdominal subcutaneous adipocytes.

Visfatin is regulated by rosiglitazone in type 2 diabetes mellitus and influenced by NFκB and JNK in human abdominal subcutaneous adipocytes.

Visfatin has been proposed as an insulin-mimicking adipocytokine, predominantly secreted from adipose tissue and correlated with obesity. However, recent studies suggest visfatin may act as a proinflammatory cytokine. Our studies sought to determine the significance of this adipocytokine and its pot...

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Bibliographic Details
Main Authors: Kirsty C McGee, Alison L Harte, Nancy F da Silva, Nasser Al-Daghri, Steven J Creely, Christine M Kusminski, Gyanendra Tripathi, Paul L Levick, Manish Khanolkar, Marc Evans, Madhu V Chittari, Vinod Patel, Sudhesh Kumar, Philip G McTernan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3111427?pdf=render

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