Role of Protein Mannosylation in the Candida tropicalis-Host Interaction

Role of Protein Mannosylation in the Candida tropicalis-Host Interaction

Mannans are components of the fungal wall attached to proteins via N- or O-linkages. In Candida albicans, Och1 is an α1,6-mannosyltransferase that adds the first mannose unit to the N-linked mannan outer chain; whereas Pmr1 is an ion pump that imports Mn2+ into the Golgi lumen. This cation is the co...

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Bibliographic Details
Main Authors: Marco J. Hernández-Chávez, Diana M. Clavijo-Giraldo, Ádám Novák, Nancy E. Lozoya-Pérez, José A. Martínez-Álvarez, Roberta Salinas-Marín, Nahúm V. Hernández, Iván Martínez-Duncker, Attila Gácser, Héctor M. Mora-Montes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
cell wall
innate immunity
host-fungus interplay
virulence
protein glycosylation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02743/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02743/full

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