Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice

Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice

<p>Abstract</p> <p>Background</p> <p>HO-1 participates in the degradation of heme. Its products can exert unique cytoprotective effects. Numerous tumors express high levels of HO-1 indicating that this enzyme might be a potential therapeutic target. In this study we dec...

Full description

Bibliographic Details
Main Authors: Jozkowicz Alicja, Was Halina, Issat Tadeusz, Salwa Pawel, Szokalska Angelika, Bil Jacek, Winiarska Magdalena, Bugajski Marek, Nowis Dominika, Dulak Jozef, Stoklosa Tomasz, Golab Jakub
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/197

Similar Items

Similar Items