Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment.

Despite intensive antibiotic treatment, Pseudomonas aeruginosa often persists in the airways of cystic fibrosis (CF) patients for decades, and can do so without antibiotic resistance development. Using high-throughput screening assays of bacterial survival after treatment with high concentrations of...

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Bibliographic Details
Main Authors: Jennifer A Bartell, David R Cameron, Biljana Mojsoska, Janus Anders Juul Haagensen, Tacjana Pressler, Lea M Sommer, Kim Lewis, Søren Molin, Helle Krogh Johansen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009112