Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study

Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study

Abstract Background Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) carry significant morbidity and mortality. AECOPD treatment remains limited. High molecular weight hyaluronan (HMW-HA) is a glycosaminoglycan sugar, which is a physiological constituent of the lung extracellula...

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Bibliographic Details
Main Authors:	Flavia Galdi, Claudio Pedone, Christopher A. McGee, Margaret George, Annette B. Rice, Shah S. Hussain, Kadambari Vijaykumar, Evan R. Boitet, Guillermo J. Tearney, John A. McGrath, Audrey R. Brown, Steven M. Rowe, Raffaele A. Incalzi, Stavros Garantziotis
Format:	Article
Language:	English
Published:	BMC 2021-02-01
Series:	Respiratory Research
Online Access:	https://doi.org/10.1186/s12931-020-01610-x

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