A High-Fat Diet Exacerbates the Course of Experimental Trypanosoma cruzi Infection That Can Be Mitigated by Treatment with Simvastatin

A High-Fat Diet Exacerbates the Course of Experimental Trypanosoma cruzi Infection That Can Be Mitigated by Treatment with Simvastatin

The protozoan Trypanosoma cruzi is responsible for triggering a damage immune response in the host cardiovascular system. This parasite has a high affinity for host lipoproteins and uses the low-density lipoprotein (LDL) receptor for its invasion. Assuming that the presence of LDL cholesterol in tis...

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Main Authors: Débora Maria Soares de Souza, Guilherme de Paula Costa, Ana Luísa Junqueira Leite, Daniela Silva de Oliveira, Kelerson Mauro de Castro Pinto, Sílvia Elvira Barros Farias, Natália Figueiroa Simões, Nívia Carolina Nogueira de Paiva, Paula Melo de Abreu Vieira, Camilo Adalton Mariano da Silva, Vivian Paulino Figueiredo, Ana Paula de Jesus Menezes, Andre Talvani
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/1230461

Internet

http://dx.doi.org/10.1155/2020/1230461

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