Comparative Study of Lytic Activity and Specificity of Anthrax Bacteriophages Gamma A-26, K VIEV, VA-9 and Fah-VNIIVV&M Batches

• Main Authors: T. M. Golovinskaya, N. P. Buravtseva, O. I. Tsygankova, E. I. Eremenko
• Format: Article
• Language: Russian
• Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2011-06-01
• Series: Проблемы особо опасных инфекций
• Subjects: anthrax bacteriophages; lytic activity; specificity; <i>bacillus anthracis</i>; saprophytes
• Online Access: https://journal.microbe.ru/jour/article/view/674

Studied are diagnostic properties of four anthrax bacteriophages. Indicated are various spectra of specific lytic activity and specificity of bacteriophages Gamma A-26, K VIEV, VA-9 and Fah-VNIIVV&M. K VIEV, VA-9 bacteriophages with wide spectrum of specific activity possess relatively low specificity. On the contrary, Fah-VNIIVV&M bacteriophage with high specificity exhibited narrow spectrum of specific lytic activity. Gamma A-26 bacteriophage is proposed for application as a diagnostic one, as it lyzes B. anthracis strains of all types, its specificity being equal to 90 %.