Synthesis and biological evaluation of di- and tri-substituted imidazoles as safer anti-inflammatory-antifungal agents

Synthesis and biological evaluation of di- and tri-substituted imidazoles as safer anti-inflammatory-antifungal agents

Purpose: In view of the potential pharmacophoric nature of imidazole nucleus, two series of imidazole derivatives, 2,4-disubstituted-1 H-imidazoles (2a-m) and 1,2,4-trisubstituted-1 H-imidazoles (3a-m), were synthesized with an aim of obtaining dual acting compounds i.e., anti-inflammatory and antif...

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Bibliographic Details
Main Authors:	Asif Husain, Sushma Drabu, Nitin Kumar, M M Alam, Sandhya Bawa
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2013-01-01
Series:	Journal of Pharmacy and Bioallied Sciences
Subjects:	Analgesic antifungal anti-inflammatory imidazole ulcerogenicity
Online Access:	http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2013;volume=5;issue=2;spage=154;epage=161;aulast=Husain

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