circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade

circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade

Abstract Background Precise quantification of microRNA is challenging since circulating mRNA and rRNA in the blood are usually degraded. Therefore, it is necessary to identify specific biomarkers for ovarian cancer. This study aimed to investigate candidate circular RNAs (circRNAs) involved in the p...

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Bibliographic Details
Main Authors: San-Gang Wu, Ping Zhou, Jian-Xian Chen, Jian Lei, Li Hua, Yong Dong, Min Hu, Chen-Lu Lian, Li-Chao Yang, Juan Zhou
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cancer Cell International
Subjects:
Ovarian cancer
Circ-PTK2
miR-639
FOXC1
Epithelial–mesenchymal transition
Online Access:https://doi.org/10.1186/s12935-021-01985-x

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