Alpha7 acetylcholine receptor autoantibodies are rare in sera of patients diagnosed with schizophrenia or bipolar disorder.

Alpha7 acetylcholine receptor autoantibodies are rare in sera of patients diagnosed with schizophrenia or bipolar disorder.

The α7 acetylcholine receptor (AChR) has been linked with the onset of psychotic symptoms and we hypothesized therefore that it might also be an autoimmune target. Here, we describe a new radioimmunoassay (RIA) using iodine 125-labelled α-bungarotoxin and membrane extract from transfected HEK293 cel...

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Bibliographic Details
Main Authors: Carolin Hoffmann, Jo Stevens, Shenghua Zong, Daan van Kruining, Abhishek Saxena, Cem İsmail Küçükali, Erdem Tüzün, Nazlı Yalçınkaya, Marc De Hert, Emiliano González-Vioque, Celso Arango, Jon Lindstrom, Marc H De Baets, Bart P F Rutten, Jim van Os, Peter Molenaar, Mario Losen, Pilar Martinez-Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208412

Internet

https://doi.org/10.1371/journal.pone.0208412

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