ACE2 enhance viral infection or viral infection aggravate the underlying diseases

ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' und...

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Main Authors:	Shaolei Teng, Qiyi Tang
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Series:	Computational and Structural Biotechnology Journal
Subjects:	Coronavirus Infectious Disease-19 Severe Acute Respiratory Syndrome Coronavirus −2 Angiotensin converting enzyme 2 Single Nucleotide Polymorphism Underlying diseases Health disparity
Online Access:	http://www.sciencedirect.com/science/article/pii/S200103702030355X

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spelling	doaj-fdad1d467d8c4b119f15906f4adb65462021-01-02T05:08:53ZengElsevierComputational and Structural Biotechnology Journal2001-03702020-01-011821002106ACE2 enhance viral infection or viral infection aggravate the underlying diseasesShaolei Teng0Qiyi Tang1Department of Biology, Howard University, 415 College St. NW, Washington, DC 20059 USA; Corresponding authors.Howard University College of Medicine, 520 W Street NW, Washington, DC 20059 USA; Corresponding authors.ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' underlying diseases and ages. Therefore, particular care to the patients with underlying diseases is needed during the treatment of COVID-19 patients.http://www.sciencedirect.com/science/article/pii/S200103702030355XCoronavirus Infectious Disease-19Severe Acute Respiratory Syndrome Coronavirus −2Angiotensin converting enzyme 2Single Nucleotide PolymorphismUnderlying diseasesHealth disparity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Shaolei Teng Qiyi Tang
spellingShingle	Shaolei Teng Qiyi Tang ACE2 enhance viral infection or viral infection aggravate the underlying diseases Computational and Structural Biotechnology Journal Coronavirus Infectious Disease-19 Severe Acute Respiratory Syndrome Coronavirus −2 Angiotensin converting enzyme 2 Single Nucleotide Polymorphism Underlying diseases Health disparity
author_facet	Shaolei Teng Qiyi Tang
author_sort	Shaolei Teng
title	ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_short	ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_full	ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_fullStr	ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_full_unstemmed	ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_sort	ace2 enhance viral infection or viral infection aggravate the underlying diseases
publisher	Elsevier
series	Computational and Structural Biotechnology Journal
issn	2001-0370
publishDate	2020-01-01
description	ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' underlying diseases and ages. Therefore, particular care to the patients with underlying diseases is needed during the treatment of COVID-19 patients.
topic	Coronavirus Infectious Disease-19 Severe Acute Respiratory Syndrome Coronavirus −2 Angiotensin converting enzyme 2 Single Nucleotide Polymorphism Underlying diseases Health disparity
url	http://www.sciencedirect.com/science/article/pii/S200103702030355X
work_keys_str_mv	AT shaoleiteng ace2enhanceviralinfectionorviralinfectionaggravatetheunderlyingdiseases AT qiyitang ace2enhanceviralinfectionorviralinfectionaggravatetheunderlyingdiseases
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ACE2 enhance viral infection or viral infection aggravate the underlying diseases

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