The main actors involved in extending the invertebrate life span

Classical invertebrate models, i.e., Drosophila melanogaster and Caenorhabditis elegans, have provided the keys to understand the life span regulation. In the present paper we summarize the mechanisms involved in this process with particular emphasis on the role of the fly fat body. It is interesti...

Full description

Bibliographic Details
Main Authors:	E Ottaviani, A Franchini, M Mandrioli
Format:	Article
Language:	English
Published:	University of Modena and Reggio Emilia 2014-02-01
Series:	Invertebrate Survival Journal
Subjects:	Drosophila melanogaster insulin/IGF-1-like pathway fat body gut microbiota longevity
Online Access:	https://isj02.unimore.it/index.php/ISJ/article/view/308

id	doaj-fda7fd4834dd47f4ab4700d3988e2fdf
record_format	Article
spelling	doaj-fda7fd4834dd47f4ab4700d3988e2fdf2020-12-02T18:38:53ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2014-02-01111The main actors involved in extending the invertebrate life spanE Ottaviani0A Franchini1M Mandrioli2Department of Animal Biology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Animal Biology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Animal Biology, University of Modena and Reggio Emilia, Modena, Italy Classical invertebrate models, i.e., Drosophila melanogaster and Caenorhabditis elegans, have provided the keys to understand the life span regulation. In the present paper we summarize the mechanisms involved in this process with particular emphasis on the role of the fly fat body. It is interesting to note that pathways which lead to an extension of life span are highly conserved in animals so that “longevity pathways” identified in invertebrates provide templates for the identification of genes and drugs that regulate longevity and diseases also in other animals, including mammals. https://isj02.unimore.it/index.php/ISJ/article/view/308Drosophila melanogasterinsulin/IGF-1-like pathwayfat bodygut microbiotalongevity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	E Ottaviani A Franchini M Mandrioli
spellingShingle	E Ottaviani A Franchini M Mandrioli The main actors involved in extending the invertebrate life span Invertebrate Survival Journal Drosophila melanogaster insulin/IGF-1-like pathway fat body gut microbiota longevity
author_facet	E Ottaviani A Franchini M Mandrioli
author_sort	E Ottaviani
title	The main actors involved in extending the invertebrate life span
title_short	The main actors involved in extending the invertebrate life span
title_full	The main actors involved in extending the invertebrate life span
title_fullStr	The main actors involved in extending the invertebrate life span
title_full_unstemmed	The main actors involved in extending the invertebrate life span
title_sort	main actors involved in extending the invertebrate life span
publisher	University of Modena and Reggio Emilia
series	Invertebrate Survival Journal
issn	1824-307X
publishDate	2014-02-01
description	Classical invertebrate models, i.e., Drosophila melanogaster and Caenorhabditis elegans, have provided the keys to understand the life span regulation. In the present paper we summarize the mechanisms involved in this process with particular emphasis on the role of the fly fat body. It is interesting to note that pathways which lead to an extension of life span are highly conserved in animals so that “longevity pathways” identified in invertebrates provide templates for the identification of genes and drugs that regulate longevity and diseases also in other animals, including mammals.
topic	Drosophila melanogaster insulin/IGF-1-like pathway fat body gut microbiota longevity
url	https://isj02.unimore.it/index.php/ISJ/article/view/308
work_keys_str_mv	AT eottaviani themainactorsinvolvedinextendingtheinvertebratelifespan AT afranchini themainactorsinvolvedinextendingtheinvertebratelifespan AT mmandrioli themainactorsinvolvedinextendingtheinvertebratelifespan AT eottaviani mainactorsinvolvedinextendingtheinvertebratelifespan AT afranchini mainactorsinvolvedinextendingtheinvertebratelifespan AT mmandrioli mainactorsinvolvedinextendingtheinvertebratelifespan
_version_	1724403405888159744

The main actors involved in extending the invertebrate life span

Similar Items