The Effect of Different Ester Chain Modifications of Two Guaianolides for Inhibition of Colorectal Cancer Cell Growth

The Effect of Different Ester Chain Modifications of Two Guaianolides for Inhibition of Colorectal Cancer Cell Growth

Several sesquiterpene lactones (STLs) have been tested as lead drugs in cancer clinical trials. Salograviolide-<b>A</b> (Sal-<b>A)</b> and salograviolide-<b>B</b> (Sal-<b>B)</b> are two STLs that have been isolated from <i>Centaurea ainetensis<...

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Bibliographic Details
Main Authors: Lamis Al Aaraj, Berthe Hayar, Zaynab Jaber, Walid Saad, Najat A. Saliba, Nadine Darwiche, Tarek Ghaddar
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
guaianolides
sesquiterpene lactones
ester derivatives
cell growth activity
colorectal cancer
p53
Online Access:https://www.mdpi.com/1420-3049/26/18/5481

Internet

https://www.mdpi.com/1420-3049/26/18/5481

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