The Action of inVestigational Drugs of Brucella abortus in the L- and S-forms on the Subpopulations of Blood Cells and Peritoneal Fluid of White Mice (Communication 2)

• Main Authors: S. A. Vityazeva, T. P. Starovoitova, V. I. Dubrovina, L. M. Mikhailov, K. Yu. Yastremskaya, L. E. Tokareva, N. L. Barannikova, S. V. Balakhonov
• Format: Article
• Language: Russian
• Published: Numikom LLC 2015-04-01
• Series: Эпидемиология и вакцинопрофилактика
• Subjects: l- и s-формы; бруцеллез; вакцина; кровь; перитонеальная жидкость; интоксикация; l- and s-forms; brucellosis; vaccine; blood; peritoneal fluid; intoxication
• Online Access: https://www.epidemvac.ru/jour/article/view/47
• ISSN: 2073-3046; 2619-0494

We have estimated the effects of the Brucella abortus 19 ВА inactivated vaccine, thermo extracts of Brucella abortus I-206 in the L- and S-forms and corpuscular antigen of Brucella abortus I-206 in L-form on the population and subpopulation structure of blood cells and peritoneal fluid of white mice. It was showed that the antigen preparations of Brucella abortus I-206 in L-form didn't caused endogenous intoxication of the organism of experimental animals in distinction from the inactivated vaccine of Brucella abortus 19 BA.