APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY

APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY

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Research into molecular apoptosis mechanisms in patients with cardio-vascular diseases is one of the pressing issues in modern medicine. Many mechanisms of this phenomenon still remain unexamined, the role of inductors and regulators in cardiomyocyte apoptosis has not yet been fully explained. This...

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Main Author: A.G. Gasanov
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2009-08-01
Series:Pediatričeskaâ Farmakologiâ
Online Access:https://www.pedpharma.ru/jour/article/view/985
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spelling doaj-fd911bdde057419a8748e9e13e247c3b2021-07-28T16:32:35ZengPaediatrician Publishers, LLCPediatričeskaâ Farmakologiâ1727-57762500-30892009-08-01643034980APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCYA.G. Gasanov0Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowResearch into molecular apoptosis mechanisms in patients with cardio-vascular diseases is one of the pressing issues in modern medicine. Many mechanisms of this phenomenon still remain unexamined, the role of inductors and regulators in cardiomyocyte apoptosis has not yet been fully explained. This review summarizes research data that analyze the role that various groups of cell death inductors and regulators, such as FasL, Fas-R and mitochondrial apoptosis factors. Influence of the Bcl-2 protein family as apoptosis regulators is described. Developments in programmed cell death are reviewed.Key words: apoptosis, cell death mechanisms, mitochondria, cardiamyocytes.https://www.pedpharma.ru/jour/article/view/985
collection DOAJ
language English
format Article
sources DOAJ
author A.G. Gasanov
spellingShingle A.G. Gasanov
APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY
Pediatričeskaâ Farmakologiâ
author_facet A.G. Gasanov
author_sort A.G. Gasanov
title APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY
title_short APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY
title_full APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY
title_fullStr APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY
title_full_unstemmed APOPTOSIS AND CHRONIC CARDIAC INSUFFICIENCY
title_sort apoptosis and chronic cardiac insufficiency
publisher Paediatrician Publishers, LLC
series Pediatričeskaâ Farmakologiâ
issn 1727-5776
2500-3089
publishDate 2009-08-01
description Research into molecular apoptosis mechanisms in patients with cardio-vascular diseases is one of the pressing issues in modern medicine. Many mechanisms of this phenomenon still remain unexamined, the role of inductors and regulators in cardiomyocyte apoptosis has not yet been fully explained. This review summarizes research data that analyze the role that various groups of cell death inductors and regulators, such as FasL, Fas-R and mitochondrial apoptosis factors. Influence of the Bcl-2 protein family as apoptosis regulators is described. Developments in programmed cell death are reviewed.Key words: apoptosis, cell death mechanisms, mitochondria, cardiamyocytes.
url https://www.pedpharma.ru/jour/article/view/985
work_keys_str_mv AT aggasanov apoptosisandchroniccardiacinsufficiency
_version_ 1721265825013301248

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